MATHEMATICAL MODELS FOR CHROMOSOMAL INVERSIONS
نویسندگان
چکیده
منابع مشابه
Nineteen paracentric chromosomal inversions in mice.
Using mutagens on sperm and spermatids we have produced nineteen chromosomal inversions in mice. The levels of radiation and chemical mutagen we used induced inversions in about one per cent of the animals screened. Nine inversions have been transmitted through successive generations, and the particular frequency of first meiotic anaphase bridges manifested by each inversion remained constant. ...
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Zinc finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) provide powerful platforms for genome editing in plants and animals. Typically, a single nuclease is sufficient to disrupt the function of protein-coding genes through the introduction of microdeletions or insertions that cause frameshifts within an early coding exon. However, interrogating the function of...
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Chromosomal inversions have been repeatedly involved in local adaptation in a large number of animals and plants. The ecological and behavioral plasticity of Anopheles species-human malaria vectors-is mirrored by high amounts of polymorphic inversions. The adaptive significance of chromosomal inversions has been consistently attested by strong and significant correlations between their frequenc...
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Chromosomal inversions allow genetic divergence of locally adapted populations by reducing recombination between chromosomes with different arrangements. Divergence between populations (or hybridization between species) is expected to leave signatures in the neutral genetic diversity of the inverted region. Quantitative expectations for these patterns, however, have not been obtained. Here, we ...
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Railway crew scheduling problem is a substantial part of the railway transportation planning, which aims to find the optimal combination of the trip sequences (pairings), and assign them to the crew complements. In this problem, each trip must be covered by at least one pairing. The multiple-covered trips lead to impose useless transfers called “transitions”. In this study, a new ma...
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ژورنال
عنوان ژورنال: Genetics
سال: 1967
ISSN: 1943-2631
DOI: 10.1093/genetics/55.4.783